Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids

Two major isoforms of human carboxylesterases (CEs) are found in metabolically active tissues, CES1 and CES2. These hydrolytic enzymes are involved in xenobiotic and endobiotic metabolism. CES1 is abundantly expressed in human liver and monocytes/macrophages, including the THP1 cell line; CES2 is ex...

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Autori principali: Crow, J. Allen, Herring, Katye L., Xie, Shuqi, Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787731/
https://ncbi.nlm.nih.gov/pubmed/19761868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.09.002
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