Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids

Two major isoforms of human carboxylesterases (CEs) are found in metabolically active tissues, CES1 and CES2. These hydrolytic enzymes are involved in xenobiotic and endobiotic metabolism. CES1 is abundantly expressed in human liver and monocytes/macrophages, including the THP1 cell line; CES2 is ex...

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Autores principales: Crow, J. Allen, Herring, Katye L., Xie, Shuqi, Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787731/
https://ncbi.nlm.nih.gov/pubmed/19761868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.09.002
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