Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages

Cholesteryl esters are hydrolyzed by cholesteryl ester hydrolase (CEH) yielding free cholesterol for export from macrophages. Hence, CEH has an important regulatory role in macrophage reverse cholesterol transport (RCT). CEH and human carboxylesterase 1 (CES1) appear to be the same enzyme. CES1 is i...

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Detalhes bibliográficos
Main Authors: Crow, J. Allen, Middleton, Brandy L., Borazjani, Abdolsamad, Hatfield, M. Jason, Potter, Philip M., Ross, Matthew K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574903/
https://ncbi.nlm.nih.gov/pubmed/18762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.07.005
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