Catabolism of 4-Hydroxy-2-trans-Nonenal by THP1 Monocytes/Macrophages and Inactivation of Carboxylesterases by this Lipid Electrophile

Oxidative stress in cells and tissues leads to the formation of an assortment of lipid electrophiles, such as the quantitatively important 4-hydroxy-2-trans-nonenal (HNE). Although this cytotoxic aldehyde is atherogenic the mechanisms involved are unclear. We hypothesize that elevated HNE levels can...

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Bibliografische gegevens
Hoofdauteurs: Borazjani, Abdolsamad, Edelmann, Mariola J., Hardin, Katelyn L., Herring, Katye L., Crow, J. Allen, Ross, Matthew K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186858/
https://ncbi.nlm.nih.gov/pubmed/21878322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2011.08.007
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