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In Silico Design and Evaluation of Carboxylesterase Inhibitors
Carboxylesterases (CEs) are important enzymes that catalyze biological detoxification, hydrolysis of certain pesticides, and metabolism of many esterified drugs. The development of inhibitors for CE has many potential uses, including increasing drug lifetime and altering biodistrubution; reducing or...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593733/ https://ncbi.nlm.nih.gov/pubmed/23487487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1584/jpestics.R10-06 |
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