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In Silico Design and Evaluation of Carboxylesterase Inhibitors

Carboxylesterases (CEs) are important enzymes that catalyze biological detoxification, hydrolysis of certain pesticides, and metabolism of many esterified drugs. The development of inhibitors for CE has many potential uses, including increasing drug lifetime and altering biodistrubution; reducing or...

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Main Authors: Stoddard, Shana V., Yu, Xiaozhen, Potter, Philip M., Wadkins, Randy M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593733/
https://ncbi.nlm.nih.gov/pubmed/23487487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1584/jpestics.R10-06
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