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In Silico Design and Evaluation of Carboxylesterase Inhibitors

Carboxylesterases (CEs) are important enzymes that catalyze biological detoxification, hydrolysis of certain pesticides, and metabolism of many esterified drugs. The development of inhibitors for CE has many potential uses, including increasing drug lifetime and altering biodistrubution; reducing or...

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Hlavní autoři: Stoddard, Shana V., Yu, Xiaozhen, Potter, Philip M., Wadkins, Randy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593733/
https://ncbi.nlm.nih.gov/pubmed/23487487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1584/jpestics.R10-06
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