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In Silico Design and Evaluation of Carboxylesterase Inhibitors
Carboxylesterases (CEs) are important enzymes that catalyze biological detoxification, hydrolysis of certain pesticides, and metabolism of many esterified drugs. The development of inhibitors for CE has many potential uses, including increasing drug lifetime and altering biodistrubution; reducing or...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593733/ https://ncbi.nlm.nih.gov/pubmed/23487487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1584/jpestics.R10-06 |
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