Llwytho...
The development and application of small molecule modulators of SF3b as therapeutic agents for cancer
The identification of potent spliceosome modulators that demonstrate antitumor activity indicates that this complex may be a target for drug development. Several natural products have been demonstrated to bind to the SF3b1 subunit of this macromolecule and these agents modulate alternative RNA splic...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596818/ https://ncbi.nlm.nih.gov/pubmed/22885522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2012.07.013 |
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