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Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems

Circadian timekeeping systems drive oscillatory gene expression to regulate essential cellular and physiological processes. When the systems are perturbed, pathological consequences ensue and disease risks rise. A growing number of small-molecule modulators have been reported to target circadian sys...

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Bibliografiske detaljer
Udgivet i:Annu Rev Pharmacol Toxicol
Main Authors: Chen, Zheng, Yoo, Seung-Hee, Takahashi, Joseph S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076890/
https://ncbi.nlm.nih.gov/pubmed/28968186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010617-052645
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