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Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems

Circadian timekeeping systems drive oscillatory gene expression to regulate essential cellular and physiological processes. When the systems are perturbed, pathological consequences ensue and disease risks rise. A growing number of small-molecule modulators have been reported to target circadian sys...

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Dades bibliogràfiques
Publicat a:Annu Rev Pharmacol Toxicol
Autors principals: Chen, Zheng, Yoo, Seung-Hee, Takahashi, Joseph S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076890/
https://ncbi.nlm.nih.gov/pubmed/28968186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010617-052645
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