Principles of agonist recognition in Cys-loop receptors

Por Lynagh, Timothy, Pless, Stephan A.
Publicado em 2014

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

Por Pless, Stephan A., Lynch, Joseph W.
Publicado em 2009

Magnitude of a Conformational Change in the Glycine Receptor β1-β2 Loop Is Correlated with Agonist Efficacy

Por Pless, Stephan A., Lynch, Joseph W.
Publicado em 2009

How an intrinsic ligand tunes the activity of a potassium channel

Por Khoo, Keith K., Pless, Stephan A.
Publicado no J Gen Physiol (2018)

Ligand- and Subunit-specific Conformational Changes in the Ligand-binding Domain and the TM2-TM3 Linker of α1 β2 γ2 GABA(A) Receptors

Por Wang, Qian, Pless, Stephan A., Lynch, Joseph W.
Publicado em 2010

Unique Contributions of an Arginine Side Chain to Ligand Recognition in a Glutamate-gated Chloride Channel

Por Lynagh, Timothy, Komnatnyy, Vitaly V., Pless, Stephan A.
Publicado no J Biol Chem (2017)

PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels

Por Kim, Robin Y., Pless, Stephan A., Kurata, Harley T.
Publicado no Proc Natl Acad Sci U S A (2017)

Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology

Por Pless, Stephan A, Kim, Robin Y, Ahern, Christopher A, Kurata, Harley T
Publicado no J Physiol (2015)

Contributions of Counter-Charge in a Potassium Channel Voltage-Sensor Domain

Por Pless, Stephan A., Galpin, Jason D., Niciforovic, Ana P., Ahern, Christopher A.
Publicado no Nat Chem Biol (2011)

Contributions of Conserved Residues at the Gating Interface of Glycine Receptors

Por Pless, Stephan A., Leung, Ada W. Y., Galpin, Jason D., Ahern, Christopher A.
Publicado em 2011

Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

Por Rivera-Acevedo, Ricardo E., Pless, Stephan A., Schwarz, Stephan K.W., Ahern, Christopher A.
Publicado em 2013

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

Por Pless, Stephan A, Galpin, Jason D, Niciforovic, Ana P, Kurata, Harley T, Ahern, Christopher A
Publicado em 2013

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

Por Pless, Stephan A., Niciforovic, Ana P., Galpin, Jason D., Nunez, John-Jose, Kurata, Harley T., Ahern, Christopher A.
Publicado em 2013

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

Por Pless, Stephan A., Elstone, Fisal D., Niciforovic, Ana P., Galpin, Jason D., Yang, Runying, Kurata, Harley T., Ahern, Christopher A.
Publicado em 2014

Atomic basis for therapeutic activation of neuronal potassium channels

Por Kim, Robin Y., Yau, Michael C., Galpin, Jason D., Seebohm, Guiscard, Ahern, Christopher A., Pless, Stephan A., Kurata, Harley T.
Publicado no Nat Commun (2015)

A selectivity filter at the intracellular end of the acid-sensing ion channel pore

Por Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Wulf, Matthias, Komnatnyy, Vitaly V, Colding, Janne M, Allen, Toby W, Pless, Stephan A
Publicado no eLife (2017)

A Cation-π Interaction in the Binding Site of the Glycine Receptor Is Mediated by a Phenylalanine Residue

Por Pless, Stephan A., Millen, Kat S., Hanek, Ariele P., Lynch, Joseph W., Lester, Henry A., Lummis, Sarah C. R., Dougherty, Dennis A.
Publicado em 2008

Intermediate state trapping of a voltage sensor

Por Lacroix, Jérôme J., Pless, Stephan A., Maragliano, Luca, Campos, Fabiana V., Galpin, Jason D., Ahern, Christopher A., Roux, Benoît, Bezanilla, Francisco
Publicado em 2012

A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists

Por Pless, Stephan A., Hanek, Ariele P., Price, Kerry L., Lynch, Joseph W., Lester, Henry A., Dougherty, Dennis A., Lummis, Sarah C. R.
Publicado em 2011

A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels

Por Zhang, Roger S., Wright, Jordan D., Pless, Stephan A., Nunez, John-Jose, Kim, Robin Y., Li, Jenny B. W., Yang, Runying, Ahern, Christopher A., Kurata, Harley T.
Publicado no J Biol Chem (2015)