A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels

ATP-sensitive potassium (K(ATP)) channels are heteromultimeric complexes of an inwardly rectifying Kir channel (Kir6.x) and sulfonylurea receptors. Their regulation by intracellular ATP and ADP generates electrical signals in response to changes in cellular metabolism. We investigated channel elemen...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Roger S., Wright, Jordan D., Pless, Stephan A., Nunez, John-Jose, Kim, Robin Y., Li, Jenny B. W., Yang, Runying, Ahern, Christopher A., Kurata, Harley T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505460/
https://ncbi.nlm.nih.gov/pubmed/25934393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631960
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