Principles of agonist recognition in Cys-loop receptors

по Lynagh, Timothy, Pless, Stephan A.
Опубликовано 2014

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

по Pless, Stephan A., Lynch, Joseph W.
Опубликовано 2009

Magnitude of a Conformational Change in the Glycine Receptor β1-β2 Loop Is Correlated with Agonist Efficacy

по Pless, Stephan A., Lynch, Joseph W.
Опубликовано 2009

How an intrinsic ligand tunes the activity of a potassium channel

по Khoo, Keith K., Pless, Stephan A.
Опубликовано в: J Gen Physiol (2018)

A tale of ligands big and small: an update on how pentameric ligand-gated ion channels interact with agonists and proteins

по Pless, Stephan A., Sivilotti, Lucia G.
Опубликовано в: Curr Opin Physiol (2019)

Ligand- and Subunit-specific Conformational Changes in the Ligand-binding Domain and the TM2-TM3 Linker of α1 β2 γ2 GABA(A) Receptors

по Wang, Qian, Pless, Stephan A., Lynch, Joseph W.
Опубликовано 2010

Unique Contributions of an Arginine Side Chain to Ligand Recognition in a Glutamate-gated Chloride Channel

по Lynagh, Timothy, Komnatnyy, Vitaly V., Pless, Stephan A.
Опубликовано в: J Biol Chem (2017)

PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels

по Kim, Robin Y., Pless, Stephan A., Kurata, Harley T.
Опубликовано в: Proc Natl Acad Sci U S A (2017)

Molecular determinants for agonist recognition and discrimination in P2X2 receptors

по Gasparri, Federica, Wengel, Jesper, Grutter, Thomas, Pless, Stephan A.
Опубликовано в: J Gen Physiol (2019)

Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology

по Pless, Stephan A, Kim, Robin Y, Ahern, Christopher A, Kurata, Harley T
Опубликовано в: J Physiol (2015)

Contributions of Counter-Charge in a Potassium Channel Voltage-Sensor Domain

по Pless, Stephan A., Galpin, Jason D., Niciforovic, Ana P., Ahern, Christopher A.
Опубликовано в: Nat Chem Biol (2011)

Contributions of Conserved Residues at the Gating Interface of Glycine Receptors

по Pless, Stephan A., Leung, Ada W. Y., Galpin, Jason D., Ahern, Christopher A.
Опубликовано 2011

Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes

по Lynagh, Timothy, Mikhaleva, Yana, Colding, Janne M., Glover, Joel C., Pless, Stephan A.
Опубликовано в: Proc Natl Acad Sci U S A (2018)

Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

по Rivera-Acevedo, Ricardo E., Pless, Stephan A., Schwarz, Stephan K.W., Ahern, Christopher A.
Опубликовано 2013

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

по Pless, Stephan A, Galpin, Jason D, Niciforovic, Ana P, Kurata, Harley T, Ahern, Christopher A
Опубликовано 2013

Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

по Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Sheikh, Zeshan Pervez, Allen, Toby W., Pless, Stephan A.
Опубликовано в: J Gen Physiol (2020)

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

по Pless, Stephan A., Niciforovic, Ana P., Galpin, Jason D., Nunez, John-Jose, Kurata, Harley T., Ahern, Christopher A.
Опубликовано 2013

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

по Pless, Stephan A., Elstone, Fisal D., Niciforovic, Ana P., Galpin, Jason D., Yang, Runying, Kurata, Harley T., Ahern, Christopher A.
Опубликовано 2014

Atomic basis for therapeutic activation of neuronal potassium channels

по Kim, Robin Y., Yau, Michael C., Galpin, Jason D., Seebohm, Guiscard, Ahern, Christopher A., Pless, Stephan A., Kurata, Harley T.
Опубликовано в: Nat Commun (2015)

Four drug-sensitive subunits are required for maximal effect of a voltage sensor–targeted KCNQ opener

по Wang, Alice W., Yau, Michael C., Wang, Caroline K., Sharmin, Nazlee, Yang, Runying Y., Pless, Stephan A., Kurata, Harley T.
Опубликовано в: J Gen Physiol (2018)