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Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain
Understanding the activation mechanism of Cys loop ion channel receptors is key to understanding their physiological and pharmacological properties under normal and pathological conditions. The ligand-binding domains of these receptors comprise inner and outer β-sheets and structural studies indicat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708881/ https://ncbi.nlm.nih.gov/pubmed/19286654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809343200 |
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