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Phosphorylation of α3 Glycine Receptors Induces a Conformational Change in the Glycine-Binding Site

[Image: see text] Inflammatory pain sensitization is initiated by prostaglandin-induced phosphorylation of α3 glycine receptors (GlyRs) that are specifically located in inhibitory synapses on spinal pain sensory neurons. Phosphorylation reduces the magnitude of glycinergic synaptic currents, thereby...

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Detalhes bibliográficos
Main Authors: Han, Lu, Talwar, Sahil, Wang, Qian, Shan, Qiang, Lynch, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798985/
https://ncbi.nlm.nih.gov/pubmed/23834509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400097j
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