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Luminescence Resonance Energy Transfer Investigation of Conformational Changes in the Ligand Binding Domain of a Kainate Receptor

The apo state structure of the isolated ligand binding domain of the GluR6 subunit and the conformational changes induced by agonist binding to this protein have been investigated by luminescence resonance energy transfer (LRET) measurements. The LRET-based distances show that agonist binding induce...

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Autori principali: Du, Mei, Rambhadran, Anu, Jayaraman, Vasanthi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556009/
https://ncbi.nlm.nih.gov/pubmed/18658129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805040200
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