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LRET investigations of conformational changes in the ligand binding domain of a functional AMPA receptor

The structural investigations using the soluble ligand binding domain of the AMPA subtype of the glutamate receptor have provided invaluable insight into the mechanistic pathway by which agonist binding to this extracellular domain mediates the formation of cation-selective channels in this protein....

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Autores principales: Gonzalez, Jennifer, Rambhadran, Anu, Du, Mei, Jayaraman, Vasanthi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630883/
https://ncbi.nlm.nih.gov/pubmed/18759455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800690b
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