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Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

Trimeric acid-sensing ion channels (ASICs) contribute to neuronal signaling by converting extracellular acidification into excitatory sodium currents. Previous work with homomeric ASIC1a implicates conserved leucine (L7′) and consecutive glycine-alanine-serine (GAS belt) residues near the middle, an...

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書目詳細資料
發表在:J Gen Physiol
Main Authors: Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Sheikh, Zeshan Pervez, Allen, Toby W., Pless, Stephan A.
格式: Artigo
語言:Inglês
出版: Rockefeller University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062507/
https://ncbi.nlm.nih.gov/pubmed/31952079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812297
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