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Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels
Trimeric acid-sensing ion channels (ASICs) contribute to neuronal signaling by converting extracellular acidification into excitatory sodium currents. Previous work with homomeric ASIC1a implicates conserved leucine (L7′) and consecutive glycine-alanine-serine (GAS belt) residues near the middle, an...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062507/ https://ncbi.nlm.nih.gov/pubmed/31952079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812297 |
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