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A selectivity filter at the intracellular end of the acid-sensing ion channel pore
Increased extracellular proton concentrations during neurotransmission are converted to excitatory sodium influx by acid-sensing ion channels (ASICs). 10-fold sodium/potassium selectivity in ASICs has long been attributed to a central constriction in the channel pore, but experimental verification i...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449180/ https://ncbi.nlm.nih.gov/pubmed/28498103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24630 |
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