A selectivity filter at the intracellular end of the acid-sensing ion channel pore

Increased extracellular proton concentrations during neurotransmission are converted to excitatory sodium influx by acid-sensing ion channels (ASICs). 10-fold sodium/potassium selectivity in ASICs has long been attributed to a central constriction in the channel pore, but experimental verification i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Wulf, Matthias, Komnatnyy, Vitaly V, Colding, Janne M, Allen, Toby W, Pless, Stephan A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Biophysics and Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449180/
https://ncbi.nlm.nih.gov/pubmed/28498103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24630
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