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Selective ion permeation involves complexation with carboxylates and lysine in a model human sodium channel
Bacterial and human voltage-gated sodium channels (Na(v)s) exhibit similar cation selectivity, despite their distinct EEEE and DEKA selectivity filter signature sequences. Recent high-resolution structures for bacterial Na(v)s have allowed us to learn about ion conduction mechanisms in these simpler...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152994/ https://ncbi.nlm.nih.gov/pubmed/30208027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006398 |
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