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Ion conduction and conformational flexibility of a bacterial voltage-gated sodium channel

Voltage-gated Na(+) channels play an essential role in electrical signaling in the nervous system and are key pharmacological targets for a range of disorders. The recent solution of X-ray structures for the bacterial channel Na(v)Ab has provided an opportunity to study functional mechanisms at the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boiteux, Céline, Vorobyov, Igor, Allen, Toby W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948317/
https://ncbi.nlm.nih.gov/pubmed/24550503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320907111
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