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A tale of ligands big and small: an update on how pentameric ligand-gated ion channels interact with agonists and proteins

Pentameric ligand-gated ion channels (pLGICs, also known as Cys-loop receptors) are a large family of ion channels expressed in all Bilateria and in several groups of bacteria and archaea. They are activated by small-molecule neurotransmitters to mediate fast transmission at many central and periphe...

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Detalhes bibliográficos
Publicado no:Curr Opin Physiol
Main Authors: Pless, Stephan A., Sivilotti, Lucia G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588529/
https://ncbi.nlm.nih.gov/pubmed/31231710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cophys.2017.12.012
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