Molecular tuning of fast gating in pentameric ligand-gated ion channels

Neurotransmitters such as acetylcholine (ACh) and glycine mediate fast synaptic neurotransmission by activating pentameric ligand-gated ion channels (LGICs). These receptors are allosteric transmembrane proteins that rapidly convert chemical messages into electrical signals. Neurotransmitters activa...

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Bibliographic Details
Main Authors: Grutter, Thomas, de Carvalho, Lia Prado, Dufresne, Virginie, Taly, Antoine, Edelstein, Stuart J., Changeux, Jean-Pierre
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312410/
https://ncbi.nlm.nih.gov/pubmed/16319224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509024102
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