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Allosteric regulation of pentameric ligand-gated ion channels: An emerging mechanistic perspective

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical messenger—a neurotransmitter—into an ion flux through the postsynaptic membrane. They are oligomeric assemblies that provide prototypical ex...

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書目詳細資料
Main Authors: Taly, Antoine, Hénin, Jérôme, Changeux, Jean-Pierre, Cecchini, Marco
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203737/
https://ncbi.nlm.nih.gov/pubmed/25478624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.29444
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