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Allosteric regulation of pentameric ligand-gated ion channels: An emerging mechanistic perspective
Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical messenger—a neurotransmitter—into an ion flux through the postsynaptic membrane. They are oligomeric assemblies that provide prototypical ex...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203737/ https://ncbi.nlm.nih.gov/pubmed/25478624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.29444 |
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