Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment

Por Piccirilli, Joseph A., Koldobskaya, Yelena
Publicado em 2011

IDENTIFICATION OF CATALYTIC METAL ION LIGANDS IN RIBOZYMES

Por Frederiksen, John K., Piccirilli, Joseph A.
Publicado em 2009

Modulation of individual steps in group I intron catalysis by a peripheral metal ion

Por Forconi, Marcello, Piccirilli, Joseph A., Herschlag, Daniel
Publicado em 2007

Thermodynamic Evidence for Negative Charge Stabilization by a Catalytic Metal Ion within an RNA Active Site

Por Sengupta, Raghuvir N., Herschlag, Daniel, Piccirilli, Joseph A.
Publicado em 2011

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

Por Sontheimer, Erik J., Gordon, Peter M., Piccirilli, Joseph A.
Publicado em 1999

The Electrostatic Character of the Ribosomal Surface Enables Extraordinarily Rapid Target Location by Ribotoxins

Por Korennykh, Alexei V, Piccirilli, Joseph A, Correll, Carl C
Publicado em 2006

Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins

Por Korennykh, Alexei V., Correll, Carl C., Piccirilli, Joseph A.
Publicado em 2007

Synthesis, Properties, and Applications of Oligonucleotides Containing an RNA Dinucleotide Phosphorothiolate Linkage

Por Li, Nan-Sheng, Frederiksen, John K., Piccirilli, Joseph A.
Publicado em 2011

Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Non-bridging Phosphorodithioate Linkage via Phosphorothioamidites

Por Li, Nan-Sheng, Frederiksen, John K., Piccirilli, Joseph A.
Publicado em 2012

Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism

Por Harris, Michael E, Piccirilli, Joseph A, York, Darrin M
Publicado no Biochim Biophys Acta (2015)

Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme

Por DasGupta, Saurja, Suslov, Nikolai B., Piccirilli, Joseph A.
Publicado no J Am Chem Soc (2017)

Synthesis and biochemical application of 2′-O-methyl-3′-thioguanosine as a probe to explore group I intron catalysis

Por Lu, Jun, Li, Nan-Sheng, Sengupta, Raghuvir, Piccirilli, Joseph A.
Publicado em 2008

A Rearrangement of the Guanosine-Binding Site Establishes an Extended Network of Functional Interactions in the Tetrahymena Group I Ribozyme Active Site

Por Forconi, Marcello, Sengupta, Raghuvir N., Piccirilli, Joseph A., Herschlag, Daniel
Publicado em 2010

Tightening of Active Site Interactions En-route to the Transition State Revealed by Single-Atom Substitution in the Guanosine-Binding Site of the Tetrahymena Group I Ribozyme

Por Forconi, Marcello, Porecha, Rishi H., Piccirilli, Joseph A., Herschlag, Daniel
Publicado em 2011

Synthesis of 2′-N-Methylamino-2′-deoxyguanosine and 2′-N,N-Dimethylamino-2′-deoxyguanosine and Their Incorporation into RNA by Phosphoramidite Chemistry

Por Dai, Qing, Sengupta, Raghuvir, Deb, Shirshendu K., Piccirilli, Joseph A.
Publicado em 2011

The DEAH-box ATPases Prp16 and Prp43 cooperate to proofread 5′ splice site cleavage during pre-mRNA splicing

Por Koodathingal, Prakash, Novak, Thaddeus, Piccirilli, Joseph A., Staley, Jonathan P.
Publicado em 2010

Functional Identification of Catalytic Metal Ion Binding Sites within RNA

Por Hougland, James L, Kravchuk, Alexander V, Herschlag, Daniel, Piccirilli, Joseph A
Publicado em 2005

Synthesis and Incorporation of the Phosphoramidite Derivative of 2′-O-Photocaged 3′-S-Thioguanosine into Oligoribonucleotides: Substrate for Probing the Mechanism of RNA Catalysis...

Por Li, Nan-Sheng, Tuttle, Nicole, Staley, Jonathan P., Piccirilli, Joseph A.
Publicado em 2014

Effect of Zn(2+) binding and enzyme active site on the transition state for RNA 2′-O-transphosphorylation interpreted through kinetic isotope effects

Por Chen, Haoyuan, Piccirilli, Joseph A., Harris, Michael E., York, Darrin M.
Publicado no Biochim Biophys Acta (2015)

Three metal ions at the active site of the Tetrahymena group I ribozyme

Por Shan, Shu-ou, Yoshida, Aiichiro, Sun, Sengen, Piccirilli, Joseph A., Herschlag, Daniel
Publicado em 1999