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Functional Identification of Catalytic Metal Ion Binding Sites within RNA

The viability of living systems depends inextricably on enzymes that catalyze phosphoryl transfer reactions. For many enzymes in this class, including several ribozymes, divalent metal ions serve as obligate cofactors. Understanding how metal ions mediate catalysis requires elucidation of metal ion...

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Detalhes bibliográficos
Main Authors: Hougland, James L, Kravchuk, Alexander V, Herschlag, Daniel, Piccirilli, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184590/
https://ncbi.nlm.nih.gov/pubmed/16092891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030277
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