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Functional Identification of Ligands for a Catalytic Metal Ion in Group I Introns

Many enzymes use metal ions within their active sites to achieve enormous rate acceleration. Understanding how metal ions mediate catalysis requires elucidation of metal ion interactions with both the enzyme and the substrate(s). The three-dimensional arrangement determined by X-ray crystallography...

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Detalhes bibliográficos
Main Authors: Forconi, Marcello, Lee, Jihee, Lee, Jungjoon K., Piccirilli, Joseph A., Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758101/
https://ncbi.nlm.nih.gov/pubmed/18517225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800519a
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