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Functional Identification of Ligands for a Catalytic Metal Ion in Group I Introns

Many enzymes use metal ions within their active sites to achieve enormous rate acceleration. Understanding how metal ions mediate catalysis requires elucidation of metal ion interactions with both the enzyme and the substrate(s). The three-dimensional arrangement determined by X-ray crystallography...

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Autors principals: Forconi, Marcello, Lee, Jihee, Lee, Jungjoon K., Piccirilli, Joseph A., Herschlag, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758101/
https://ncbi.nlm.nih.gov/pubmed/18517225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800519a
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