Three metal ions at the active site of the Tetrahymena group I ribozyme
Metal ions are critical for catalysis by many RNA and protein enzymes. To understand how these enzymes use metal ions for catalysis, it is crucial to determine how many metal ions are positioned at the active site. We report here an approach, combining atomic mutagenesis with quantitative determinat...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1999
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22911/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535916/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12299 |
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