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Functional Identification of Ligands for a Catalytic Metal Ion in Group I Introns

Many enzymes use metal ions within their active sites to achieve enormous rate acceleration. Understanding how metal ions mediate catalysis requires elucidation of metal ion interactions with both the enzyme and the substrate(s). The three-dimensional arrangement determined by X-ray crystallography...

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Détails bibliographiques
Auteurs principaux: Forconi, Marcello, Lee, Jihee, Lee, Jungjoon K., Piccirilli, Joseph A., Herschlag, Daniel
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758101/
https://ncbi.nlm.nih.gov/pubmed/18517225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800519a
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