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Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme
The Varkud satellite (VS) ribozyme catalyzes site-specific RNA cleavage and ligation reactions. Recognition of the substrate involves a kissing loop interaction between the substrate and the catalytic domain of the ribozyme resulting in a rearrangement of the substrate helix register into a so-calle...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929484/ https://ncbi.nlm.nih.gov/pubmed/28625058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b03655 |
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