NMR structure of the active conformation of the Varkud satellite ribozyme cleavage site

Substrate cleavage by the Neurospora Varkud satellite (VS) ribozyme involves a structural change in the stem-loop I substrate from an inactive to an active conformation. We have determined the NMR solution structure of a mutant stem-loop I that mimics the active conformation of the cleavage site int...

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Bibliografiske detaljer
Main Authors: Hoffmann, Bernd, Mitchell, G. Thomas, Gendron, Patrick, Major, François, Andersen, Angela A., Collins, Richard A., Legault, Pascale
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165820/
https://ncbi.nlm.nih.gov/pubmed/12782785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0832440100
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