Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme

Most of the small ribozymes, including those that have been investigated as potential therapeutic agents, appear to be rather poor catalysts. These RNAs use an internal phosphoester transfer mechanism to catalyze site-specific RNA cleavage with apparent cleavage rate constants typically <2 min(-1...

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Detaylı Bibliyografya
Asıl Yazarlar: Zamel, Ricardo, Poon, Alan, Jaikaran, Dominic, Andersen, Angela, Olive, Joan, De Abreu, Diane, Collins, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC341743/
https://ncbi.nlm.nih.gov/pubmed/14755053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305753101
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