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Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme
Most of the small ribozymes, including those that have been investigated as potential therapeutic agents, appear to be rather poor catalysts. These RNAs use an internal phosphoester transfer mechanism to catalyze site-specific RNA cleavage with apparent cleavage rate constants typically <2 min(-1...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC341743/ https://ncbi.nlm.nih.gov/pubmed/14755053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305753101 |
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