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Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme

Most of the small ribozymes, including those that have been investigated as potential therapeutic agents, appear to be rather poor catalysts. These RNAs use an internal phosphoester transfer mechanism to catalyze site-specific RNA cleavage with apparent cleavage rate constants typically <2 min(-1)....

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Zamel, Ricardo, Poon, Alan, Jaikaran, Dominic, Andersen, Angela, Olive, Joan, De Abreu, Diane, Collins, Richard A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14755053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305753101
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