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Rapid formation of a solvent-inaccessible core in the Neurospora Varkud satellite ribozyme

We have used hydroxyl radicals generated by decomposition of peroxynitrous acid to study Mg(2+)-dependent structure and folding of the Varkud satellite (VS) ribozyme. Protection from radical cleavage shows the existence of a solvent-inaccessible core, which includes nucleotides near two three-helix...

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Autori principali: Hiley, Shawna L., Collins, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125658/
https://ncbi.nlm.nih.gov/pubmed/11574478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.19.5461
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