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Modular engineering of a Group I intron ribozyme
All Group I intron ribozymes contain a conserved core region consisting of two helical domains, P4–P6 and P3–P7. Recent studies have demonstrated that the elements required for catalysis are concentrated in the P3–P7 domain. We carried out in vitro selection experiments by using three newly construc...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2002
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137077/ https://ncbi.nlm.nih.gov/pubmed/12140333 |
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