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Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme

Most of the small ribozymes, including those that have been investigated as potential therapeutic agents, appear to be rather poor catalysts. These RNAs use an internal phosphoester transfer mechanism to catalyze site-specific RNA cleavage with apparent cleavage rate constants typically <2 min(-1)....

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Zamel, Ricardo, Poon, Alan, Jaikaran, Dominic, Andersen, Angela, Olive, Joan, De Abreu, Diane, Collins, Richard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14755053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305753101
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