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Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins
α-Sarcin and ricin represent two structurally and mechanistically distinct families of site-specific enzymes that block translation by irreversibly modifying the sarcin/ricin loop (SRL) of 23S–28S rRNA. α-Sarcin family enzymes are designated as ribotoxins and act as endonucleases. Ricin family enzym...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950761/ https://ncbi.nlm.nih.gov/pubmed/17626843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.619707 |
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