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Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins

α-Sarcin and ricin represent two structurally and mechanistically distinct families of site-specific enzymes that block translation by irreversibly modifying the sarcin/ricin loop (SRL) of 23S–28S rRNA. α-Sarcin family enzymes are designated as ribotoxins and act as endonucleases. Ricin family enzym...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Korennykh, Alexei V., Correll, Carl C., Piccirilli, Joseph A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950761/
https://ncbi.nlm.nih.gov/pubmed/17626843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.619707
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