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The Electrostatic Character of the Ribosomal Surface Enables Extraordinarily Rapid Target Location by Ribotoxins

α-sarcin ribotoxins comprise a unique family of ribonucleases that cripple the ribosome by catalyzing endoribonucleolytic cleavage of ribosomal RNA at a specific location in the sarcin/ricin loop (SRL). The SRL structure alone is cleaved site-specifically by the ribotoxin, but the ribosomal context...

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Hlavní autoři: Korennykh, Alexei V, Piccirilli, Joseph A, Correll, Carl C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847776/
https://ncbi.nlm.nih.gov/pubmed/16604082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1082
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