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The Electrostatic Character of the Ribosomal Surface Enables Extraordinarily Rapid Target Location by Ribotoxins
α-sarcin ribotoxins comprise a unique family of ribonucleases that cripple the ribosome by catalyzing endoribonucleolytic cleavage of ribosomal RNA at a specific location in the sarcin/ricin loop (SRL). The SRL structure alone is cleaved site-specifically by the ribotoxin, but the ribosomal context...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847776/ https://ncbi.nlm.nih.gov/pubmed/16604082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1082 |
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