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Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Non-bridging Phosphorodithioate Linkage via Phosphorothioamidites

[Image: see text] This work describes a general method for the synthesis of oligoribonucleotides containing a site-specific non-bridging phosphorodithioate linkage via automated solid-phase synthesis using 5′-O-DMTr-2′-O-TBS-ribonucleoside 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl) phosphorothioamidites...

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Bibliografische gegevens
Hoofdauteurs: Li, Nan-Sheng, Frederiksen, John K., Piccirilli, Joseph A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500914/
https://ncbi.nlm.nih.gov/pubmed/23050987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo301834p
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