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Automated Solid-Phase Synthesis of RNA Oligonucleotides Containing a Non-bridging Phosphorodithioate Linkage via Phosphorothioamidites
[Image: see text] This work describes a general method for the synthesis of oligoribonucleotides containing a site-specific non-bridging phosphorodithioate linkage via automated solid-phase synthesis using 5′-O-DMTr-2′-O-TBS-ribonucleoside 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl) phosphorothioamidites...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500914/ https://ncbi.nlm.nih.gov/pubmed/23050987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo301834p |
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