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Solid phase synthesis of oligodeoxyribonucleoside phosphorodithioates from thiophosphoramidites.
Oligonucleoside phosphorodithioates 1 are modified DNA sequences with potential use as antisense oligonucleotides. The preparation of up to 20-mers containing all four bases by solid phase synthesis is described, with details on the preparation of the four monomer units (protected nucleoside thiopho...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1991
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329036/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1945874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.21.5843 |
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