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Solid phase synthesis of oligodeoxyribonucleoside phosphorodithioates from thiophosphoramidites.
Oligonucleoside phosphorodithioates 1 are modified DNA sequences with potential use as antisense oligonucleotides. The preparation of up to 20-mers containing all four bases by solid phase synthesis is described, with details on the preparation of the four monomer units (protected nucleoside thiopho...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1991
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329036/ https://ncbi.nlm.nih.gov/pubmed/1945874 |
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