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Solid-Phase Synthesis of RNA Analogs Containing Phosphorodithioate Linkages
The oligoribonucleotide phosphorodithioate modification (PS2-RNA) uses two sulfur atoms to replace two non-bridging oxygen atoms at an internucleotide phosphordiester backbone linkage. Like a natural phosphodiester RNA backbone linkage, a PS2-modified backbone linkage is achiral at phosphorus. PS2-R...
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| Published in: | Curr Protoc Nucleic Acid Chem |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657504/ https://ncbi.nlm.nih.gov/pubmed/28921494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.40 |
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