Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth

Por Hong, Chibo, Moorefield, K. Scott, Jun, Peter, Aldape, Kenneth D., Kharbanda, Samir, Phillips, Heidi S., Costello, Joseph F.
Publicado em 2007

3D micro-CT imaging of the Postmortem Brain

Por de Crespigny, Alex, Bou-Reslan, Hani, Nishimura, Merry C., Phillips, Heidi, Carano, Richard A. D., D’Arceuil, Helen E.
Publicado em 2008

Hominoid-specific enzyme GLUD2 promotes growth of IDH1(R132H) glioma

Por Chen, Ruihuan, Nishimura, Merry C., Kharbanda, Samir, Peale, Frank, Deng, Yuzhong, Daemen, Anneleen, Forrest, William F., Kwong, Mandy, Hedehus, Maj, Hatzivassiliou, Georgia, Friedman, Lori S., Phillips, Heidi S.
Publicado em 2014

TMEFF2 Is a PDGF-AA Binding Protein with Methylation-Associated Gene Silencing in Multiple Cancer Types Including Glioma

Por Lin, Kui, Taylor, James R., Wu, Thomas D., Gutierrez, Johnny, Elliott, J. Michael, Vernes, Jean-Michel, Koeppen, Hartmut, Phillips, Heidi S., de Sauvage, Frederic J., Meng, Y. Gloria
Publicado em 2011

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

Por Soroceanu, Liliana, Kharbanda, Samir, Chen, Ruihuan, Soriano, Robert H., Aldape, Ken, Misra, Anjan, Zha, Jiping, Forrest, William F., Nigro, Janice M., Modrusan, Zora, Feuerstein, Burt G., Phillips, Heidi S.
Publicado em 2007

Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images

Por Naeini, Kourosh M., Pope, Whitney B., Cloughesy, Timothy F., Harris, Robert J., Lai, Albert, Eskin, Ascia, Chowdhury, Reshmi, Phillips, Heidi S., Nghiemphu, Phioanh L., Behbahanian, Yalda, Ellingson, Benjamin M.
Publicado em 2013

GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and Kidney

Por Cacalano, Grace, Fariñas, Isabel, Wang, Li-Chong, Hagler, Kelly, Forgie, Alison, Moore, Mark, Armanini, Mark, Phillips, Heidi, Ryan, Anne M., Reichardt, Louis F., Hynes, Mary, Davies, Alun, Rosenthal, Arnon
Publicado em 1998

Reversing HOXA9 Oncogene Activation by PI3K Inhibition: Epigenetic Mechanism and Prognostic Significance in Human Glioblastoma

Por Costa, Bruno M., Smith, Justin S., Chen, Ying, Chen, Justin, Phillips, Heidi S., Aldape, Kenneth D., Zardo, Giuseppe, Nigro, Janice, James, C. David, Fridlyand, Jane, Reis, Rui M., Costello, Joseph F.
Publicado em 2010

BI-22 CORRELATION OF MOLECULAR SUBTYPES WITH OVERALL SURVIVAL (OS) IN AVAGLIO, A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB (BEV) PLUS RADIOTHERAPY (RT) AND TEMOZOLOMIDE (...

Por Phillips, Heidi, Sandmann, Thomas, Li, Congfen, Cloughesy, Timothy, Chinot, Olivier L., Wick, Wolfgang, Nishikawa, Ryo, Mason, Warren, Henriksson, Roger, Saran, Frank, Lai, Albert, Moore, Nicola, Hegde, Priti, Abrey, Lauren, Bourgon, Richard, Garcia, Josep, Bais, Carlos
Publicado no Neuro Oncol (2014)

Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation

Por Li, Sichen, Chou, Arthur P., Chen, Weidong, Chen, Ruihuan, Deng, Yuzhong, Phillips, Heidi S., Selfridge, Julia, Zurayk, Mira, Lou, Jerry J., Everson, Richard G., Wu, Kuan-Chung, Faull, Kym F., Cloughesy, Timothy, Liau, Linda M., Lai, Albert
Publicado em 2013

Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the...

Por Sandmann, Thomas, Bourgon, Richard, Garcia, Josep, Li, Congfen, Cloughesy, Timothy, Chinot, Olivier L., Wick, Wolfgang, Nishikawa, Ryo, Mason, Warren, Henriksson, Roger, Saran, Frank, Lai, Albert, Moore, Nicola, Kharbanda, Samir, Peale, Franklin, Hegde, Priti, Abrey, Lauren E., Phillips, Heidi S., Bais, Carlos
Publicado no J Clin Oncol (2015)

A multigene predictor of outcome in glioblastoma

Por Colman, Howard, Zhang, Li, Sulman, Erik P., McDonald, J. Matthew, Shooshtari, Nasrin Latif, Rivera, Andreana, Popoff, Sonya, Nutt, Catherine L., Louis, David N., Cairncross, J. Gregory, Gilbert, Mark R., Phillips, Heidi S., Mehta, Minesh P., Chakravarti, Arnab, Pelloski, Christopher E., Bhat, Krishna, Feuerstein, Burt G., Jenkins, Robert B., Aldape, Ken
Publicado em 2010

Laminin alpha 2 enables glioblastoma stem cell growth

Por Lathia, Justin D., Li, Meizhang, Hall, Peter E., Gallagher, Joseph, Hale, James S., Wu, Qiulian, Venere, Monica, Levy, Emily, Rani, MR Sandhya, Huang, Ping, Bae, Eunnyung, Selfridge, Julia, Cheng, Lin, Guvenc, Hacer, McLendon, Roger E., Nakano, Ichiro, Sloan, Andrew E., Phillips, Heidi S., Lai, Albert, Gladson, Candece, Bredel, Markus, Bao, Shideng, Hjelmeland, Anita B., Rich, Jeremy N.
Publicado em 2012

NFKBIA Deletion in Glioblastomas

Por Bredel, Markus, Scholtens, Denise M., Yadav, Ajay K., Alvarez, Angel A., Renfrow, Jaclyn J., Chandler, James P., Yu, Irene L.Y., Carro, Maria S., Dai, Fangping, Tagge, Michael J., Ferrarese, Roberto, Bredel, Claudia, Phillips, Heidi S., Lukac, Paul J., Robe, Pierre A., Weyerbrock, Astrid, Vogel, Hannes, Dubner, Steven, Mobley, Bret, He, Xiaolin, Scheck, Adrienne C., Sikic, Branimir I., Aldape, Kenneth D., Chakravarti, Arnab, Harsh, Griffith R.
Publicado em 2010

PDGFRA Amplification is Common in Pediatric and Adult High‐Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma

Por Phillips, Joanna J., Aranda, Derick, Ellison, David W., Judkins, Alexander R., Croul, Sidney E., Brat, Daniel J., Ligon, Keith L., Horbinski, Craig, Venneti, Sriram, Zadeh, Gelareh, Santi, Mariarita, Zhou, Shengmei, Appin, Christina L., Sioletic, Stefano, Sullivan, Lisa M., Martinez‐Lage, Maria, Robinson, Aaron E., Yong, William H., Cloughesy, Timothy, Lai, Albert, Phillips, Heidi S., Marshall, Roxanne, Mueller, Sabine, Haas‐Kogan, Daphne A., Molinaro, Annette M., Perry, Arie
Publicado em 2013

Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Por Merchant, Mark, Ma, Xiaolei, Maun, Henry R., Zheng, Zhong, Peng, Jing, Romero, Mally, Huang, Arthur, Yang, Nai-ying, Nishimura, Merry, Greve, Joan, Santell, Lydia, Zhang, Yu-Wen, Su, Yanli, Kaufman, Dafna W., Billeci, Karen L., Mai, Elaine, Moffat, Barbara, Lim, Amy, Duenas, Eileen T., Phillips, Heidi S., Xiang, Hong, Young, Judy C., Vande Woude, George F., Dennis, Mark S., Reilly, Dorothea E., Schwall, Ralph H., Starovasnik, Melissa A., Lazarus, Robert A., Yansura, Daniel G.
Publicado em 2013

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

Por Noushmehr, Houtan, Weisenberger, Daniel J., Diefes, Kristin, Phillips, Heidi S., Pujara, Kanan, Berman, Benjamin P., Pan, Fei, Pelloski, Christopher E., Sulman, Erik P., Bhat, Krishna P., Verhaak, Roel G.W., Hoadley, Katherine A., Hayes, D. Neil, Perou, Charles M., Schmidt, Heather K., Ding, Li, Wilson, Richard K., Van Den Berg, David, Shen, Hui, Bengtsson, Henrik, Neuvial, Pierre, Cope, Leslie M., Buckley, Jonathan, Herman, James G., Baylin, Stephen B., Laird, Peter W., Aldape, Kenneth
Publicado em 2010

Evidence for Sequenced Molecular Evolution of IDH1 Mutant Glioblastoma From a Distinct Cell of Origin

Por Lai, Albert, Kharbanda, Samir, Pope, Whitney B., Tran, Anh, Solis, Orestes E., Peale, Franklin, Forrest, William F., Pujara, Kanan, Carrillo, Jose A., Pandita, Ajay, Ellingson, Benjamin M., Bowers, Chauncey W., Soriano, Robert H., Schmidt, Nils O., Mohan, Sankar, Yong, William H., Seshagiri, Somasekar, Modrusan, Zora, Jiang, Zhaoshi, Aldape, Kenneth D., Mischel, Paul S., Liau, Linda M., Escovedo, Cameron J., Chen, Weidong, Nghiemphu, Phioanh Leia, James, C. David, Prados, Michael D., Westphal, Manfred, Lamszus, Katrin, Cloughesy, Timothy, Phillips, Heidi S.
Publicado em 2011

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

Por Bhat, Krishna P.L., Balasubramaniyan, Veerakumar, Vaillant, Brian, Ezhilarasan, Ravesanker, Hummelink, Karlijn, Hollingsworth, Faith, Wani, Khalida, Heathcock, Lindsey, James, Johanna D., Goodman, Lindsey D., Conroy, Siobhan, Long, Lihong, Lelic, Nina, Wang, Suzhen, Gumin, Joy, Raj, Divya, Kodama, Yoshinori, Raghunathan, Aditya, Olar, Adriana, Joshi, Kaushal, Pelloski, Christopher E., Heimberger, Amy, Kim, Se Hoon, Cahill, Daniel P., Rao, Ganesh, Den Dunnen, Wilfred F.A., Boddeke, Hendrikus W.G.M., Phillips, Heidi S., Nakano, Ichiro, Lang, Frederick F., Colman, Howard, Sulman, Erik P., Aldape, Kenneth
Publicado em 2013