GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and Kidney

Glial cell line–derived neurotrophic factor (GDNF) is a distant member of the TGFβ protein family that is essential for neuronal survival and renal morphogenesis. We show that mice who are deficient in the glycosyl-phosphatidyl inositol (GPI) -linked protein GFRα1 (GDNFRα) display deficits in the ki...

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Bibliografiska uppgifter
Huvudupphovsmän: Cacalano, Grace, Fariñas, Isabel, Wang, Li-Chong, Hagler, Kelly, Forgie, Alison, Moore, Mark, Armanini, Mark, Phillips, Heidi, Ryan, Anne M., Reichardt, Louis F., Hynes, Mary, Davies, Alun, Rosenthal, Arnon
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710137/
https://ncbi.nlm.nih.gov/pubmed/9697851
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