Deficiency of GDNF Receptor GFRα1 in Alzheimer's Neurons Results in Neuronal Death

We have recently developed aged cortical neuron cultures from autopsied human brains with Alzheimer's disease (AD). During the culturing process, we found that glutamatergic cortical neurons from the AD brain lacked a response to glial cell line-derived neurotrophic factor (GDNF), including no...

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Detalhes bibliográficos
Main Authors: Konishi, Yoshihiro, Yang, Li-Bang, He, Ping, Lindholm, Kristina, Lu, Bai, Li, Rena, Shen, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172805/
https://ncbi.nlm.nih.gov/pubmed/25253858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2582-13.2014
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