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TGFβ induces GDNF responsiveness in neurons by recruitment of GFRα1 to the plasma membrane
We have previously shown that the neurotrophic effect of glial cell line–derived neurotrophic factor (GDNF) in vitro and in vivo requires the presence of transforming growth factor (TGF)β. Using primary neurons (chick E8 ciliary) we show that the combination of GDNF plus TGFβ promotes survival, wher...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173495/ https://ncbi.nlm.nih.gov/pubmed/12370242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203115 |
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