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TGFβ induces GDNF responsiveness in neurons by recruitment of GFRα1 to the plasma membrane

We have previously shown that the neurotrophic effect of glial cell line–derived neurotrophic factor (GDNF) in vitro and in vivo requires the presence of transforming growth factor (TGF)β. Using primary neurons (chick E8 ciliary) we show that the combination of GDNF plus TGFβ promotes survival, wher...

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Bibliografiske detaljer
Main Authors: Peterziel, H., Unsicker, K., Krieglstein, K.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173495/
https://ncbi.nlm.nih.gov/pubmed/12370242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203115
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