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The first cysteine-rich domain of the receptor GFRα1 stabilizes the binding of GDNF

The GDNF (glial cell line-derived neurotrophic factor)-binding receptor GFRα1 (GDNF family receptor α1) is attached to the membrane by a GPI (glycosylphosphatidylinositol) anchor and consists of three cysteine-rich domains. The region corresponding to the second and third domains has been shown prev...

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Detalhes bibliográficos
Main Authors: Virtanen, Heidi, Yang, Jianmin, Bespalov, Maxim M., Hiltunen, Jukka O., Leppänen, Veli-Matti, Kalkkinen, Nisse, Goldman, Adrian, Saarma, Mart, Runeberg-Roos, Pia
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135013/
https://ncbi.nlm.nih.gov/pubmed/15610063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041257
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