Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

Glial cell line-derived neurotrophic factor (GDNF) is a ligand that activates, through co-receptor GDNF family receptor alpha-1 (GFRα1) and receptor tyrosine kinase “RET”, several signaling pathways crucial in the development and sustainment of multiple neuronal populations. We decided to study whet...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saarenpää, Tuulia, Kogan, Konstantin, Sidorova, Yulia, Mahato, Arun Kumar, Tascón, Igor, Kaljunen, Heidi, Yu, Liying, Kallijärvi, Jukka, Jurvansuu, Jaana, Saarma, Mart, Goldman, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415192/
https://ncbi.nlm.nih.gov/pubmed/28467503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176166
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